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Southern Chicken Spaghetti Casserole

Southern Chicken Spaghetti Casserole: A Creamy Delight!


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  • Author: Katherine
  • Total Time: 45 minutes
  • Yield: 8 servings 1x
  • Diet: Comfort Food

Description

A creamy and delicious Southern Chicken Spaghetti Casserole that combines tender chicken, spaghetti, and a rich sauce topped with cheese.


Ingredients

Scale
  • 2 cups cooked chicken (shredded, rotisserie works great)
  • 12 oz spaghetti (uncooked)
  • 1 tbsp olive oil or butter
  • 1 medium onion, diced
  • 1 green bell pepper, diced
  • 2 cloves garlic, minced
  • 1 can (10.5 oz) cream of mushroom soup
  • 1 can (10.5 oz) cream of chicken soup
  • 1 can (10 oz) Rotel tomatoes with green chilies (undrained)
  • 1 cup chicken broth (or reserved pasta water)
  • 1 tsp paprika
  • ½ tsp garlic powder
  • ½ tsp onion powder
  • ½ tsp cayenne pepper (optional, for heat)
  • Salt & pepper to taste
  • 2 cups shredded cheddar cheese (divided)
  • 1 cup shredded Monterey Jack cheese (or mozzarella)
  • ½ cup sour cream
  • 2 tbsp cream cheese (optional, for extra creaminess)
  • Crushed Ritz crackers or breadcrumbs mixed with 2 tbsp melted butter (optional)

Instructions

  1. Cook spaghetti in salted water until al dente (a little firm). Drain and set aside (reserve ½ cup pasta water if you don’t have broth).
  2. In a large skillet, heat olive oil or butter over medium heat. Add onion and bell pepper; sauté for 4–5 minutes until softened. Add garlic and cook for another 30 seconds until fragrant.
  3. Stir in cream of mushroom, cream of chicken, Rotel, chicken broth, paprika, garlic powder, onion powder, cayenne, salt & pepper. Let simmer for 5 minutes, stirring occasionally.
  4. Stir in shredded chicken, sour cream, cream cheese (if using), 1 cup cheddar, and Monterey Jack. Mix until smooth and creamy.
  5. Add cooked spaghetti to the sauce mixture and toss until well coated. Transfer mixture to a greased 9×13 casserole dish.
  6. Sprinkle remaining 1 cup cheddar cheese on top. (Optional) Add buttery cracker crumbs or breadcrumbs for crunch. Bake at 350°F (175°C) for 25–30 minutes, until hot and bubbly.
  7. Let rest for 5 minutes before serving. Garnish with parsley or green onions if desired.

Notes

  • For spice: Use hot Rotel or add extra cayenne.
  • Use rotisserie chicken to save time.
  • Swap cheeses: Pepper Jack for spice, mozzarella for a milder flavor.
  • Freezer-friendly: Assemble casserole, cover tightly, and freeze up to 2 months. Bake from frozen at 350°F for 50–55 minutes.
  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Category: Casserole
  • Method: Baking
  • Cuisine: Southern

Nutrition

  • Serving Size: 1 cup
  • Calories: 450
  • Sugar: 3g
  • Sodium: 800mg
  • Fat: 20g
  • Saturated Fat: 10g
  • Unsaturated Fat: 8g
  • Trans Fat: 0g
  • Carbohydrates: 45g
  • Fiber: 2g
  • Protein: 30g
  • Cholesterol: 80mg